A Swedish lab study released in mid-October found that the spike protein associated with the COVID-19 illness, and its experimental vaccines, enters the nucleus of cells and significantly interferes with DNA damage-repair functions compromising a person’s adaptive immunity and perhaps encouraging the formation of cancer cells.
The study, titled “SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro,” was released by the Department of Molecular Biosciences of Stockholm University, and began by discussing the enormous impact of the COVID-19 disease on the world today, and the necessity of healthy adaptive immunity for individuals to fight off the SARS–CoV–2 infection.
Yet, the researchers highlight how multiple clinical studies indicate “that patients with severe COVID–19 exhibit delayed and weak adaptive immune responses” for reasons that have remained unclear.
Offering a possible answer to this question, the authors “report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair, which is required for effective V(D)J recombination in adaptive immunity.”
“Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair,” they wrote. “Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines.”
In an online lecture explaining the study, Dr. Mobeen Syed emphasized how B cells and T cells, which are part of the adaptive immune system, each have a certain variation for attaching to a particular invading antigen. This “variability is produced by intentionally damaging the DNA [of each cell] and then repairing it.”
In addition, “when our cells are dividing, there are strict mechanisms to make sure that the DNA is correctly repaired and correctly copied and there is no damage otherwise the cell will become a cancer cell,” he said.
Two relevant DNA repair mechanisms involve enzymes which he compared to “repair workers” that operate within the nucleus of a cell. “Imagine there are repair workers in our body, in our nucleus, that would rush to the place of a DNA break and go and fix it.”
“Now imagine if these two enzymes cannot do their function. Imagine if they cannot even be produced,” he said. In such a case, when spike and nonstructural proteins are present in the nucleus, “reduced proliferation of the cells occur.”
This means, with regards to our B and T cells alone, “our capability to respond to infections will not be good,” he said.
‘We were told the vaccines do not enter the nucleus’ or change DNA
On an episode of The Highwire, journalist Jeffery Jaxen commented on how these pathogens entering the nucleus is particularly disturbing.
“The nucleus of the cell is the main control center,” he said. “Nothing should be getting in there, like a spike protein. And even at the beginning when these mRNA vaccines were getting rolled out, we were told the vaccines do not enter the nucleus. We were told they do not alter the DNA. So, this study appears to fly in the face of those statements.”
Further, Jaxson quoted the Swedish study on how the researchers analyzed “key checkpoint proteins” BRCA1 and 53BP1 for repair pathways and “found that the spike protein markedly inhibited both BRCA1 and 53BP1 foci formation.”
He continued to explain the importance of these genes, stating that women who inherit an abnormal change in the BRCA1 “have a much higher lifetime risk of developing breast cancer.”
And he secondly referred to 53BP1 as “the Guardian of the Genome,” and quoted a 2018 study titled “53BP1: A key player of DNA damage response with critical functions in cancer.”
This paper reports, “It has been extensively demonstrated that aberrant expression of 53BP1 contributes to tumor occurrence and development. 53BP1 loss of function in tumor tissues is also related to tumor progression and poor prognosis in human malignancies.”
“Since January 1, in the laboratory, I’m seeing a 20 times increase of endometrial cancers over what I see on an annual basis,” he said.
With regards to overall adaptive immunity, Cole describes, “post-vaccine, what we are seeing is a drop in your killer T-cells” which “keep all other viruses in check” leaving the patient susceptible to a variety of illnesses.
In summarizing the study’s resulting “suggestion” made by the Swedish researchers to their colleagues in the biomedical industry, Dr. Syed wrote on his lecture white board, “Do not make full length spike protein vaccines.”
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This content was originally published here.